You really should consider the Blue Ridge Mountains in North Carolina. The BRM's actually run from Virgina all the way down to south North Carolina.
We were with my family and stayed in Blowing Rock, NC (close to Boone) for the past 5 days and it was AMAZING. Such a beautiful part of the US and I highly recommend it to anyone looking for a vacation spot in the states. You can spend days just driving the Blue Ridge Parkway or you can stay in the many cabins, hotels and resorts that you can find in the small towns along the way. Our family had a house in Blowing Rock, just about 10 miles off of the Blue Ridge Parkway. I will have a full post with all the details and tons of pictures tomorrow but here is a little sneak peak-